Rationale For Considering Values And Preferences - 1447 Words

How the guideline panels use the information: rationale for considering values and preferences Values and preferences impact the strength of recommendations, together with other factors. If the variability exists for patient values, the strength of recommendation is weak, indicating recommendations may not apply to specific patient subgroup. Guideline readers and clinical practitioners need to pay special attention to weak recommendations and accompanying values and preferences under these scenarios.2 The systematic review on utilities suggested major bleeding equivalent to nonfatal pulmonary embolism; while intracranial bleed overall was 2 to 3 times worse than major bleed or pulmonary embolism. This relative importance helps guideline panels to weigh the balance of benefits and risks and make the decision accordingly. 16 Considered as significant factors in producing recommendations, the extent to which the values and preferences vary and the extent to which the panellists are confident about the estimates and their variation can influence the strength of the recommendation. If the patient values and preferences are uncertain, or vary across different patient subgroups, the strength of recommendation should be weak. Was there any recommendations influenced by local values and preferences The local values and preferences contributed to the formulating of recommendations. 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